Sleep Medicine Reviews
Volume 14, Issue 4 , Pages 239-247, August 2010

Problems associated with short sleep: Bridging the gap between laboratory and epidemiological studies

  • Michael A. Grandner

      Affiliations

    • Center for Sleep and Respiratory Neurobiology, Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, 125 S. 31st Street, Philadelphia, PA 19104, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 215 746 4815; fax: +1 215 746 4814.
  • ,
  • Nirav P. Patel

      Affiliations

    • Center for Sleep and Respiratory Neurobiology, Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, 125 S. 31st Street, Philadelphia, PA 19104, USA
    • Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA, USA
  • ,
  • Philip R. Gehrman

      Affiliations

    • Center for Sleep and Respiratory Neurobiology, Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, 125 S. 31st Street, Philadelphia, PA 19104, USA
    • Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
  • ,
  • Michael L. Perlis

      Affiliations

    • Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
  • ,
  • Allan I. Pack

      Affiliations

    • Center for Sleep and Respiratory Neurobiology, Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, 125 S. 31st Street, Philadelphia, PA 19104, USA

Received 19 January 2009; received in revised form 21 August 2009; accepted 1 September 2009.

Summary 

Existing data from laboratory studies suggest a number of negative consequences of acute reductions in sleep time. Also, epidemiological data suggest links between shorter self-reported sleep duration and negative health outcomes. These bodies of work are growing, revealing several key points of convergence and opportunities for future exploration. In addition, they begin to highlight possible problems experienced by “short sleepers,” who sleep approximately 6h or less per night. While it is likely that this group is heterogeneous, comprised both of individuals with less need for sleep and those not sleeping enough, the laboratory and epidemiological findings point towards directions that can be more fully explored in verified short sleepers. This paper discusses problems associated with the terminology used to describe “short sleep,” summarizes laboratory studies exploring neurobehavioral performance, metabolism and obesity, and psychological health and epidemiological studies exploring mortality risk, obesity and metabolism, cardiovascular disease, and general health/psychosocial stress, describes studies of verified short sleepers and explores areas of convergence, laying out possible future directions.

Keywords: Sleep, Sleep deprivation, Epidemiology, Short sleepers, Neurobehavioral performance, Cardiovascular, Metabolism, Obesity, Psychological health, Mortality

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PII: S1087-0792(09)00091-4

doi:10.1016/j.smrv.2009.08.001

Sleep Medicine Reviews
Volume 14, Issue 4 , Pages 239-247, August 2010