Sleep Medicine Reviews
Volume 13, Issue 6 , Pages 427-436 , December 2009

A systematic review of continuous positive airway pressure for obstructive sleep apnoea–hypopnoea syndrome

  • Catriona McDaid

      Affiliations

    • Centre for Reviews and Dissemination, University of York, York, UK
    • Corresponding Author InformationCorresponding author at: Centre for Reviews and Dissemination, University of York, Heslington, York YO10 5DD, UK. Tel.: +44 (0)1904 321 040; fax: +44 (0)1904 321 041.
    • ,
  • Kate H. Durée

      Affiliations

    • Centre for Reviews and Dissemination, University of York, York, UK
    • Tel.: +44 (0)1904 321 036; fax: +44 (0)1904 321 041.
    • ,
  • Susan C. Griffin

      Affiliations

    • Centre for Health Economics, University of York, York, UK
    • Tel.: +44 (0)1904 321 419; fax: +44 (0)1904 321 402.
    • ,
  • Helen L.A. Weatherly

      Affiliations

    • Centre for Health Economics, University of York, York, UK
    • Tel.: +44 (0)1904 321 447; fax: +44 (0)1904 321 402.
    • ,
  • John R. Stradling

      Affiliations

    • Oxford Centre for Respiratory Medicine, Oxford Radcliffe Hospital, Oxford, UK
    • Tel.: +44 (0)1865 225 236; fax: +44 (0)1865 22 5221.
    • ,
  • Robert J.O. Davies

      Affiliations

    • Oxford Centre for Respiratory Medicine, Oxford Radcliffe Hospital, Oxford, UK
    • Tel.: +44 (0)1865 225 230; fax: +44 (0)1865 225 205.
    • ,
  • Mark J. Sculpher

      Affiliations

    • Centre for Health Economics, University of York, York, UK
    • Tel.: +44 (0)1904 321 440; fax: +44 (0)1904 321 402.
    • ,
  • Marie E. Westwood

      Affiliations

    • Centre for Reviews and Dissemination, University of York, York, UK
    • Tel.: +44 (0)1904 321 091; fax: +44 (0)1904 321 041.

References* 

  1. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993;328:1230–1235
  2. Davies RJ, Stradling JR. The epidemiology of sleep apnoea. Thorax. 1996;51:S65–S70
  3. Lindberg E, Gislason T. Epidemiology of sleep-related obstructive breathing. Sleep Med Rev. 2000;4:411–433
  4. Moyer CA, Sonnad SS, Garetz SL, Helman JI, Chervin RD. Quality of life in obstructive sleep apnea: a systematic review of the literature. Sleep Med. 2001;2:477–491
  5. Engleman HM, Douglas NJ. Sleep, driving and the workplace. Clin Med. 2005;5:113–117
  6. Sassani A, Findley LJ, Kryger M, Goldlust E, George C, Davidson TM. Reducing motor-vehicle collisions, costs, and fatalities by treating obstructive sleep apnea syndrome. Sleep. 2004;27:453–458
  7. Lindberg E, Carter N, Gislason T, Janson C. Role of snoring and daytime sleepiness in occupational accidents. Am J Respir Crit Care Med. 2001;164:2031–2035
  8. Saunamaki T, Jehkonen M. A review of executive functions in obstructive sleep apnea syndrome. Acta Neurol Scand. 2007;115:1–11
  9. McNicholas WT, Bonsignore MR, the Management Committee of EU Cost Action B26 . Sleep apnoea as an independent risk factor for cardiovascular disease. Current evidence, basic mechanisms and research priorities. Eur Respir J. 2007;29:156–178
  10. Shamsuzzaman AS, Gersh BJ, Somers VK. Obstructive sleep apnea: implications for cardiac and vascular disease. JAMA. 2003;290:1906–1914
  11. Robinson GV, Stradling JR, Davies RJ. Sleep 6: obstructive sleep apnoea/hypopnoea syndrome and hypertension. Thorax. 2004;59:1089–1094
  12. Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with obstructive sleep apnoea–hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet. 2005;365:1046–1053
  13. Gibson GJ. Obstructive sleep apnoea syndrome: underestimated and undertreated. Br Med Bull. 2004;72:49–64
  14. Pack AI, Platt AB, Pien GW. Does untreated obstructive apnea lead to death?. Sleep. 2008;31:1067–1068
  15. Marshall NS, Wong KKH, Liu PY, Cullen SRJ, Knuiman MW, Grunstein RR. Sleep apnea as an independent risk factor for all-cause mortality: the Busselton Health Study. Sleep. 2008;31:1079–1085
  16. Young T, Finn L, Peppard PE, Szklo-Coxe M, Austin D, Nieto FJ, et al. Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin Sleep Cohort. Sleep. 2008;31:1071–1078
  17. Mc Daid C, Griffin S, Weatherly H, Duree K, van der Burgt M, van Hout S, et al. Continuous positive airway pressure devices for the treatment of obstructive sleep apnoea–hypopnoea syndrome: a systematic review and economic analysis. Health Technol Assess. 2009;13:1–274
  18. Weatherly HLA, Griffin SC, Mc Daid C, Duree KH, Davies RJO, Stradling JR, et al. An economic analysis of continuous positive airway pressure for the treatment of obstructive sleep apnea–hypopnoea syndrome. Int J Technol Assess Health Care. 2009;25:26–34
  19. Arand D, Bonnet M, Hurwitz T, Mitler M, Rosa R, Sangal RB. The clinical use of the MSLT and MWT. Sleep. 2005;28:123–144
  20. Wright J, Johns R, Watt I, Melville A, Sheldon T. Health effects of obstructive sleep apnoea and the effectiveness of continuous positive airways pressure: a systematic review of the research evidence. BMJ. 1997;314:851–860
  21. Patel SR, White DP, Malhotra A, Stanchina ML, Ayas NT. Continuous positive airway pressure therapy for treating sleepiness in a diverse population with obstructive sleep apnea: results of a meta-analysis. Arch Intern Med. 2003;163:565–571
  22. Marshall NS, Barnes M, Travier N, Campbell AJ, Pierce RJ, McEvoy RD, et al. Continuous positive airway pressure reduces daytime sleepiness in mild to moderate obstructive sleep apnoea: a meta-analysis. Thorax. 2006;61:430–434
  23. Giles TL, Lasserson TJ, Smith BJ, White J, Wright J, Cates CJ. Continuous positive airways pressure for obstructive sleep apnoea in adults. Cochrane Database of Systematic Reviews. 2006;3:Art. No.: CD001106
  24. Curtin F, Altman DG, Elbourne D. Meta-analysis combining parallel and cross-over clinical trials. I: continuous outcomes. Stat Med. 2002;21:2131–2144
  25. Elbourne DR, Altman DG, Higgins JPT, Curtin F, Worthington HV, Vail A. Meta-analyses involving cross-over trials: methodological issues. Int J Epidemiol. 2002;31:140–149
  26. Centre for Reviews and Dissemination . Undertaking systematic reviews of research on effectiveness: CRD's guidance for those carrying out or commissioning reviews. Available from: 2nd ed.. York: Centre for Reviews and Dissemination; 2001;http://www.york.ac.uk/inst/crd/report4.htm
  27. Review Manager (RevMan). 4.2 for Windows ed. [program] Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration; 2003.
  28. Higgins JPT, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557–560
  29. Jenkinson C, Davies RJ, Mullins R, Stradling JR. Comparison of therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised prospective parallel trial. Lancet. 1999;353:2100–2105
  30. West SD, Nicoll DJ, Wallace TM, Matthews DR, Stradling JR. The effect of CPAP on insulin resistance and HBA1C in people with obstructive sleep apnoea and type 2 diabetes: a randomised controlled trial. Thorax. 2006;61:ii54
  31. Barnes M, McEvoy RD, Banks S, Tarquinio N, Murray CG, Vowles N, et al. Efficacy of positive airway pressure and oral appliance in mild to moderate obstructive sleep apnea. Am J Respir Crit Care Med. 2004;170:656–664
  32. Lam B, Sam K, Mok W, Cheung MT, Fong DY, Lam JC, et al. A randomised study of three non-surgical treatments in mild to moderate obstructive sleep apnoea. Thorax. 2007;62:354–359
  33. Norman D, Loredo JS, Nelesen RA, Ancoli-Israel S, Mills PJ, Ziegler MG, et al. Effects of continuous positive airway pressure versus supplemental oxygen on 24-hour ambulatory blood pressure. Hypertension. 2006;47:840–845
  34. Coughlin SR, Mawdsley L, Mugarza JA, Wilding JPH, Calverley PM. Cardiovascular and metabolic effects of CPAP in obese men with OSA. [epub ahead of print] Eur Respir J. 2007;
  35. Becker HF, Jerrentrup A, Ploch T, Grote L, Penzel T, Sullivan CE, et al. Effect of nasal continuous positive airway pressure treatment on blood pressure in patients with obstructive sleep apnea. Circulation. 2003;107:68–73
  36. Pepperell JC, Ramdassingh-Dow S, Crosthwaite N, Mullins R, Jenkinson C, Stradling JR, et al. Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised parallel trial. Lancet. 2002;359:204–210
  37. Arias MA, Garcia-Rio F, Alonso-Fernandez A, Mediano O, Martinez I, Villamor J. Obstructive sleep apnea syndrome affects left ventricular diastolic function: effects of nasal continuous positive airway pressure in men. Circulation. 2005;112:375–383
  38. Hui DS, To KW, Ko FW, Fok JP, Chan MC, Ngai JC, et al. Nasal CPAP reduces systemic blood pressure in patients with obstructive sleep apnoea and mild sleepiness. Thorax. 2006;61:1083–1090
  39. Arias MA, Garcia-Rio F, Alonso-Fernandez A, Martinez I, Villamor J. Pulmonary hypertension in obstructive sleep apnoea: effects of continuous positive airway pressure. A randomized, controlled cross-over study. Eur Heart J. 2006;27:1106–1113
  40. Barbe F, Mayoralas LR, Duran J, Masa JF, Maimo A, Montserrat JM, et al. Treatment with continuous positive airway pressure is not effective in patients with sleep apnea but no daytime sleepiness. a randomized, controlled trial. Ann Intern Med. 2001;134:1015–1023
  41. Becker HF, Jerrentrup A, Ploch T, Grote L, Penzel T, Peter JH. Effect of therapeutic and subtherapeutic nasal continuous positive airway pressure (nCPAP) treatment on blood pressure in obstructive sleep apnea (OSA). Sleep Med. 2003;4:S3
  42. Campos-Rodriguez F, Grilo-Reina A, Perez-Ronchel J, Merino-Sanchez M, Gonzalez-Benitez MA, Beltran-Robles M, et al. Effect of continuous positive airway pressure on ambulatory BP in patients with sleep apnea and hypertension: a placebo-controlled trial. Chest. 2006;129:1459–1467
  43. Robinson GV, Smith DM, Langford BA, Davies RJ, Stradling JR. Continuous positive airway pressure does not reduce blood pressure in nonsleepy hypertensive OSA patients. Eur Respir J. 2006;27:1229–1235
  44. Barnes M, Houston D, Worsnop CJ, Neill AM, Mykytyn IJ, Kay A, et al. A randomized controlled trial of continuous positive airway pressure in mild obstructive sleep apnea. Am J Respir Crit Care Med. 2002;165:773–780
  45. Engleman HM, Gough K, Martin SE, Kingshott RN, Padfield PL, Douglas NJ. Ambulatory blood pressure on and off continuous positive airway pressure therapy for the sleep apnea/hypopnea syndrome: effects in “non-dippers”. Sleep. 1996;19:378–381
  46. Faccenda JF, Mackay TW, Boon NA, Douglas NJ. Randomized placebo-controlled trial of continuous positive airway pressure on blood pressure in the sleep apnea-hypopnea syndrome. Am J Respir Crit Care Med. 2001;163:344–348
  47. Monasterio C, Vidal S, Duran J, Ferrer M, Carmona C, Barbe F, et al. Effectiveness of continuous positive airway pressure in mild sleep apnea–hypopnea syndrome. Am J Respir Crit Care Med. 2001;164:939–943
  48. Dimsdale JE, Loredo JS, Profant J. Effect of continuous positive airway pressure on blood pressure: a placebo trial. Hypertension. 2000;35:144–147
  49. Bonnet MH. ACNS clinical controversy: MSLT and MWT have limited clinical utility. J Clin Neurophysiol. 2006;23:50–58
  50. Littner MR, Kushida CA, Wise MS, Davila D, Morgenthaler TI, Lee-Chiong T, et al. Practice parameters for clinical use of the multiple sleep latency test and the maintenance of wakefulness test. Sleep. 2005;28:113–121
  51. O'Brien E, Asmar R, Beilin L, Imai Y, Mallion JM, Mancia G, et al. European Society of Hypertension recommendations for conventional, ambulatory and home blood pressure measurement. J Hypertens. 2003;21:821–848
  52. Haentjens P, Van Meerhaeghe A, Moscariello A, De Weerdt S, Poppe K, Dupont A, et al. The impact of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syndrome. Arch Intern Med. 2007;167:757–765
  53. Henke KG, Grady JJ, Kuna ST. Effect of nasal continuous positive airway pressure on neuropsychological function in sleep apnea-hypopnea syndrome. A randomized, placebo-controlled trial. Am J Respir Crit Care Med. 2001;163:911–917
  54. Marshall NS, Neill AM, Campbell AJ, Sheppard DS. Randomised controlled crossover trial of humidified continuous positive airway pressure in mild obstructive sleep apnoea. Thorax. 2005;60:427–432
  55. Montserrat JM, Ferrer M, Hernandez L, Farre R, Vilagut G, Navajas D, et al. Effectiveness of CPAP treatment in daytime function in sleep apnea syndrome: a randomized controlled study with an optimized placebo. Am J Respir Crit Care Med. 2001;164:608–613
  56. Engleman HM, Martin SE, Deary IJ, Douglas NJ. Effect of continuous positive airway pressure treatment on daytime function in sleep apnoea/hypopnoea syndrome. Lancet. 1994;343:572–575
  57. Engleman HM, Martin SE, Deary IJ, Douglas NJ. Effect of CPAP therapy on daytime function in patients with mild sleep apnoea/hypopnoea syndrome. Thorax. 1997;52:114–119
  58. Engleman HM, Martin SE, Kingshott RN, Mackay TW, Deary IJ, Douglas NJ. Randomised placebo controlled trial of daytime function after continuous positive airway pressure (CPAP) therapy for the sleep apnoea/hypopnoea syndrome. Thorax. 1998;53:341–345
  59. Engleman HM, Kingshott RN, Wraith PK, Mackay TW, Deary IJ, Douglas NJ. Randomized placebo-controlled crossover trial of continuous positive airway pressure for mild sleep apnea/hypopnea syndrome. Am J Respir Crit Care Med. 1999;159:461–467
  60. Ballester E, Badia JR, Hernandez L, Carrasco E, de Pablo J, Fornas C, et al. Evidence of the effectiveness of continuous positive airway pressure in the treatment of sleep apnea/hypopnea syndrome. Am J Respir Crit Care Med. 1999;159:495–501
  61. Chakravorty I, Cayton RM, Szczepura A. Health utilities in evaluating intervention in the sleep apnoea/hypopnoea syndrome. Eur Respir J. 2002;20:1233–1238
  62. Redline S, Adams N, Strauss ME, Roebuck T, Winters M, Rosenberg C. Improvement of mild sleep-disordered breathing with CPAP compared with conservative therapy. Am J Respir Crit Care Med. 1998;157:858–865
  63. Engleman HM, McDonald JP, Graham D, Lello GE, Kingshott RN, Coleman EL, et al. Randomized crossover trial of two treatments for sleep apnea/hypopnea syndrome: continuous positive airway pressure and mandibular repositioning splint. Am J Respir Crit Care Med. 2002;166:855–859
  64. Fleetham JA, Lowe A, Vazquez JC, Ferguson K, Flemons W, Remmers JA. A long term randomized parallel multicentre study of an oral appliance vs nCPAP in the treatment of obstructive sleep apnea. Am J Respir Crit Care Med. 1997;155:A939
  65. Ferguson KA, Ono T, Lowe AA, al Majed S, Love LL, Fleetham JA. A short-term controlled trial of an adjustable oral appliance for the treatment of mild to moderate obstructive sleep apnoea. Thorax. 1997;52:362–368
  66. Tan YK, L'Estrange PR, Luo YM, Smith C, Grant HR, Simonds AK, et al. Mandibular advancement splints and continuous positive airway pressure in patients with obstructive sleep apnoea: a randomized cross-over trial. Eur J Orthod. 2002;24:239–249

PII: S1087-0792(09)00018-5

doi: 10.1016/j.smrv.2009.02.004

Sleep Medicine Reviews
Volume 13, Issue 6 , Pages 427-436 , December 2009

Article Tools

* Image Usage & Resolution