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Sleep Medicine Reviews
Volume 13, Issue 6
, Pages 385-401
, December 2009
The clinical and pathophysiological relevance of REM sleep behavior disorder in neurodegenerative diseases
References*
- . The international classification of sleep disorders. 2nd ed.. Westchester, IL: American Academy of Sleep Medicine; 2005;
- . REM sleep behavior disorder: clinical, developmental, and neuroscience perspectives 16 years after its formal identification in SLEEP. Sleep. 2002;25:120–138
- . Locus coeruleus et sommeil paradoxal. CR Soc Biol. 1965;159:895–899
- . REM sleep without atonia after lesions of the medial medulla. Neurosci Lett. 1989;98:159–165
- . Chronical behavioral disorders of human REM sleep: a new category of parasomnia. Sleep. 1986;9:293–308
- . Motor dyscontrol in narcolepsy: rapid-eye-movement (REM) sleep without atonia and REM sleep behavior disorder. Ann Neurol. 1992;32:3–10
- . Delayed emergence of a parkinsonian disorder in 38% of 29 older men initially diagnosed with idiopathic rapid eye movement sleep behavior disorder. Neurology. 1996;46:388–393
- Rapid-eye-movement sleep behaviour disorder as an early marker for a neurodegenerative disease: a descriptive study. Lancet Neurol. 2006;5:572–577
- Postuma RB, Gagnon JF, Vendette M, Fantini Ml, Massicote- Marquez J, Montplaisir J. Quantifying the risk of neurodegenerative disease in idiopathic REM sleep behavior disorder. Neurology 2008 (in press).
- . REM sleep behavior disorder in Parkinson's disease and other parkinsonian disorders. Sleep Med. 2004;5:195–199
- . Review of rapid eye movement behavior sleep disorders. Curr Neurol Neurosci Rep. 2004;4:157–163
- . REM sleep bevaviour disorder. Neurol Sci. 2005;26(Suppl):186–192
- . Idiopathic REM sleep behavior disorder. Toward a better nosologic definition. Neurology. 2005;64:780–786
- . REM sleep behaviour disorder: clinical profiles and pathophysiology. Int Rev Psychiatry. 2005;17:293–300
- . Update on the pharmacology of REM sleep behavior disorder. Neurology. 2006;67:742–747
- . Rapid-eye-movement sleep behaviour disorder and neurodegenerative diseases. Lancet Neurol. 2006;5:424–432
- . REM sleep behaviour disorder in Parkinson's disease. J Neurol. 2007;254(Suppl. 4):8–14
- . REM sleep disorders and parkinsonism. J Neurol. 2007;254(Suppl. 5):56–60
- . Symptomatic REM sleep behaviour disorder. Neurol Sci. 2007;28(Suppl. 1):S21–S36
- . Rapid eye movement sleep behavior disorder. Ann Pharmacother. 2007;41:1833–1841
- . Idiopathic rapid eye movement sleep behaviour disorder. Neurol Sci. 2007;28(Suppl. 1):15–20
- Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. Brain. 2007;130:2770–2788
- . Sleep disturbances in patients with parkinsonism. Nat Clin Pract Neurol. 2008;4:254–266
- . Sleep disorders. Cognitive dysfunction in REM sleep behavior disorder. Rev Neurol Dis. 2008;5:162–163
- . Rapid eye movement disorder in children and adolescents. Dev Med Child Neurol. 2008;50:728–732
- . Violent behavior during sleep. J Clin Psychiatry. 1997;20:340–348
- Characteristics of idiopathic REM sleep behavior disorder and that associated with MSA and PD. Neurology. 2005;65:247–252
- . REM sleep behavior disorder and epileptic phenomena: clinical aspects of comorbidity. Epilepsia. 2006;47(Suppl. 5):78–81
- . REM sleep behavior disorder in elderly subjects with epilepsy. Frequency and clinical aspects of the comorbidity. Epilepsy Res. 2007;77:128–133
- . The importance of sleep medicine consultation for diagnosis of REM sleep behavior disorder in most patients with Parkinson's disease. Sleep Med. 2002;3:537–538
- . Prominent eye movements during NREM sleep and REM sleep behavior disorder associated with fluoxetine treatment of depression and obsessive-compulsive disorder. Sleep. 1992;15:226–235
- . Serotonergic antidepressants are associated with REM sleep without atonia. Sleep. 2004;27(2):317–321
- . Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism. Neurology. 2003;60:113–115
- . Rapid eye movement sleep behavior disorder: demographic, clinical and laboratory findings in 93 cases. Brain. 2000;123:331–339
- . REM sleep parasomnias. Neurol Clin. 1996;14:697–720
- Restoration of normal muscle control in Parkinson's disease during REM sleep. Brain. 2007;130:450–456
- REM sleep behavior disorders in multiple system atrophy. Neurology. 1997;48:1094–1097
- . Absence of alterations in serum sex hormones levels in idiopathic REM sleep behavior disorder. Sleep. 2007;30:803–806
- . Testosterone not associated with violent dreams or REM sleep behavior disorder in men with Parkinson's. Mov Disord. 2007;22:411–414
- REM sleep behavior disorder and REM sleep without atonia in Parkinson's disease. Neurology. 2002;59:585–589
- Sleep-related injury in the elderly. An epidemiological study in Hong Kong. Sleep. 2000;23:513–517
- . Phenomenology of dreams in Parkinson's disease. Mov Disord. 2007;22:198–202
- . Severe obstructive sleep apnea/hypopnea mimicking REM sleep behavior disorder. Sleep. 2005;28:203–206
- . Sonambulism in Parkinson's disease: another sleep disorder to deal with. Neurology. 2002;58(Suppl. 3):A432
- . Sleepwalking in patients with parkinsonism. Arch Neurol. 2007;64:1524–1527
- . REM behavior disorder associated with epileptic seizures. Neurology. 2005;64:883–884
- . Sleep-related violence, injury, and REM sleep behavior disorder in PD. Neurology. 1999;52:1924
- Sleep apnea syndrome in Parkinson's disease. A case-control study in 49 patients. Mov Disord. 2005;20:1413–1418
- . Diagnosis of REM sleep behavior disorder by video-polysomnography study: is one night enough?. Sleep. 2008;31:1179–1185
- . The international classification of sleep disorders. Diagnostic and coding manual. Rochester, MN: American Sleep Disorders Association; 1990;
- . Polysomnographic features of REM sleep behavior disorder: development of a scoring method. Neurology. 1992;42:1371–1374
- . Validation of a polysomnographic score for REM sleep behavior disorder. Sleep. 2005;28:993–997
- Quantification of electromyographic activity during REM sleep in multiple muscles in REM sleep behavior disorder. Sleep. 2008;31:724–731
- . EMG variance during polysomnography as an assessment for REM sleep behavior disorder. Sleep. 2007;30:1771–1778
- Quantification of tonic and phasic muscle activity in REM sleep behavior disorder. J Clin Neurophysiol. 2008;25:48–55
- A quantitative statistical analysis of the submental muscle EMG amplitude during sleep in normal controls and patients with REM sleep behavior disorder. J Sleep Res. 2008;17:89–100
- . Quantification of electromyographic activity during sleep: a phasic electromyographic metric. J Clin Neurophysiol. 2006;23:59–67
- Increased muscle activity during rapid eye movement sleep correlates with decrease of striatal presynaptic dopamine transporters. IPT and IBZM SPECT imaging in subclinical and clinically manifest idiopathic REM sleep behavior disorder, Parkinson's disease, and controls. Sleep. 2003;26:507–512
- . REM sleep behaviour disorder: clinical and pathophysiological findings. Sleep Med Rev. 1997;1:57–69
- . The effects of pramipexole in REM sleep behavior disorder. Neurology. 2003;61:1418–1420
- Video analysis of motor events in REM sleep behavior disorder. Mov Disord. 2007;22:1464–1470
- Rapid eye movement disorder in parkinsonism with PARKIN mutations. Ann Neurol. 2004;56:599–603
- Dullery C. Colanezapm. In: Dullery C, editor. Therapeutic drugs, vol. 1. Edinburgh: Churchill Livingstone. p. C299–C303.
- . Melatonin as a therapy in REM sleep behavior disorder patients: an open-labeled pilot study on the possible influence of melatonin on REM-sleep regulation. Mov Disord. 1999;14:507–511
- . Melatonin for treatment of REM sleep behavior disorder in neurological disorders: results in 14 patients. Sleep Med. 2003;4:281–284
- . Bisoprolol-induced REM sleep behavior disorder. Am J Med. 1999;107:390–392
- . Olfactory deficit in idiopathic rapid eye movements sleep behavior disorder. Brain Res Bull. 2006;70:386–390
- . Potential early markers of Parkinson disease in idiopathic REM sleep behavior disorder. Neurology. 2006;66:845–851
- . Neuropsychological assessment in idiopathic REM sleep behavior disorder. Neurology. 2004;62:41–45
- Slow-wave sleep and delta power in rapid eye movement sleep behavior disorder. Ann Neurol. 2005;57:277–282
- . Cardiac autonomic activity during wakefulness and sleep in REM sleep behavior disorder. Sleep. 1996;19:367–369
- . Reduced cardiac 123I-MBIG scintigraphy in idiopathic REM sleep behavior disorder. Neurology. 2006;67:2236–2238
- . Reduced striatal dopamine transporters in idiopathic rapid eye movement sleep behaviour disorder. Brain. 2000;123:1155–1160
- Stockner H, Iranzo A, Seppi K, Serradell M, Gschliesser V, Sojer M, et al. Midbrain hyperechogenicity in idiopathic REM sleep behavior disorder. Mov disord 2009 (in press).
- Assessment of idiopathic REM sleep behavior disorder by transcranial sonography, olfactory function test and FP-CIT-SPECT. Mov Disord. 2008;23:596–599
- Incidental Lewy body disease in a patient with REM sleep behavior disorder. Neurology. 1995;45:709–712
- Insights into REM sleep behavior disorder pathophysiology in brainstem-predominant Lewy body disease. Sleep Med. 2007;8:60–64
- . REM sleep behaviour disorder (RBD) delayed emergence of parkinsonism and/or dementia in 65% of older men initially diagnosed with idiopathic RBD, and an analysis of the maximum and minimum tonic and/or phasic electromyographic abnormalities found during REM sleep. Sleep. 2003;26(Suppl.):A316
- Sixty-four percent of patients with idiopathic REM sleep behavior disorder developed a neurological disorder after a mean clinical follow-up of seven years. Sleep. 2008;31(Suppl):A280
- . Multiple system atrophy. Lancet Neurol. 2004;3:93–103
- Consensus statement on the diagnosis of multiple system atrophy. J Neurol Sci. 1999;163:94–98
- . Brainstem in multiple system atrophy: clinicopathological correlations. Cell Mol Neurobiol. 2003;23:519–526
- . REM sleep motor dysfunction in multiple system atrophy: with special emphasis on sleep talk as its early clinical manifestation. J Neurol Neurosurg Psychiatry. 1997;63:678–681
- Red flags for MSA. Mov Disord. 2008;23:1093–1099
- Sleep disorders in multiple system atrophy: a correlative video-polysomnographic study. Sleep Med. 2004;5:21–30
- . Pathological description of a non-motor variant of multiple system atrophy. J Neurol Neurosurg Psychiatry. 2008;79:1399–1400
- . Sages 1–2 Non rapid eye movement sleep behavior disorder associated with dementia: anew parasomnia?. Mov Disord. 2005;20:1223–1227
- Status dissociatus after surgery for tegmental ponto-mesencephalic cavernoma: a state dependent disorder of motor control during sleep. Mov Disord. 2004;19:719–723
- . Depletion of mesopontine cholinergic and sparing raphe neurons in multiple system atrophy. Neurology. 2002;59:944–946
- Mesopontine cholinergic neuron involvement in Lewy body dementia and multiple system atrophy. Neurology. 2008;70:368–373
- Long-term effect of CPAP in the treatment of nocturnal stridor in multiple system atrophy. Neurology. 2004;63:930–932
- . The diagnosis of Parkinson's disease. Lancet Neurol. 2006;5:75–86
- . Postmortem studies in Parkinson's disease. Is it possible to detect brain areas for specific symptoms?. J Neural Transm. 1999;56(Suppl.):1–29
- . Polysomnographic measures in Parkinson's disease: a comparison between patients with and without REM sleep disturbances. Wien Klin Wochenschr. 2001;113:249–253
- . Progressive sleep destructuring in Parkinson's disease. A polysomnographic study in 46 patients. Sleep Med. 2005;6:313–318
- . Sleep-related violence, injury, and REM sleep behavior disorder in Parkinson's disease. Neurology. 1998;51:526–529
- . REM sleep behavior disorder and Parkinson's disease (PD): relationship to PD onset and treatment. Sleep. 2002;25:A494
- REM sleep behaviour disorder in Parkinson's disease: a questionnaire-based study. Neurol Sci. 2005;25:316–321
- Relationship between visual hallucinations and REM sleep behavior disorder in patients with Parkinson's disease. Clin Neurol Neurosurg. 2007;109:862–867
- . Occurrence and clinical correlates of REM sleep behaviour disorder in patients with Parkinson's disease over time. J Neurol Neurosurg Psychiatry. 2007;79:387–391
- . Manifestations of Parkinson disease differ in association with REM sleep behavior disorder. Mov Disord. 2008;15:1665–1672
- . Relation between subtype of Parkinson's disease and REM sleep behavior disorder. Sleep Med. 2007;8:779–783
- . REM sleep behavior disorder in Parkinson's disease is associated with specific motor features. J Neurol Neurosurg Psychiatry. 2008;79:1117–1121
- Association between waking EEG slowing and REM sleep behavior in PD without dementia. Neurology. 2004;62:401–406
- REM sleep behavior disorder predicts cognitive impairment in Parkinson disease without dementia. Neurology. 2007;69:1843–1849
- . REM sleep behavior disorder predicts cognitive impairment in Parkinson disease without dementia (letter). Neurology. 2008;71:955–956
- . Sensitivity analysis of the clinical criteria for REM behavior disorder (RBD) in Parkinson's disease. Neurology. 2002;58(Suppl. 3):A434
- . REM sleep behavior disorder in sleep-disordered patients with versus without Parkinson's disease: is there a need for polysomnography?. J Neurol Sci. 2001;186:7–11
- Lack of effects of pramipexole on REM sleep behavior disorder in Parkinson's disease. Sleep. 2008;31:1418–1421
- Improvement of sleep architecture in PD with subthalamic stimulation. Neurology. 2000;55:1732–1734
- . Sleep symptoms and polysomnographic architecture in advanced Parkinson's disease after chronic bilateral subthalamic stimulation. J Neurol Neurosurg Psychiatr. 2002;72:661–664
- Dementia with Lewy bodies. Lancet Neurol. 2004;3:19–28
- Diagnosis and management of dementia with Lewy bodies. Third report of the DLB consortium. Neurology. 2005;65:1863–1872
- . Dementia with Lewy bodies. Neurol Clin. 2007;25:741–760
- Clinical diagnostic criteria for dementia associated with Parkinson's disease. Mov Disord. 2007;22:1689–1707
- . Cognitive profiles of individual patients with Parkinson's disease and dementia: comparison with dementia with Lewy bodies and Alzheimer's disease. Mov Disord. 2006;21:337–342
- REM sleep behavior disorder and degenerative dementia. An association likely reflecting Lewy body disease. Neurology. 1998;51:363–370
- REM sleep behavior disorder and dementia. Cognitive differences when compared with AD. Neurology. 1999;52:951–957
- Dementia with Lewy bodies may present as dementia with REM sleep behavior disorder without parkinsonism or hallucinations. J Int Neuropsychol Soc. 2002;8:907–914
- . Synucleinopathy pathology and REM sleep behavior disorder plus dementia or parkinsonism. Neurology. 2003;61:40–45
- . REM sleep behavior disorder in Parkinson's disease and dementia with Lewy bodies. J Geriatr Psychiatry Neurol. 2004;17:146–157
- . Sleep disturbances in dementia with Lewy bodies involve more than REM sleep behavior disorder. Neurology. 2003;(Suppl1):A79
- DLB fluctuations. Specific features that reliably differentiate DLB from AD and normal aging. Neurology. 2004;62:181–187
- . Neuropsychological profile of mild cognitive impairment in patients with REM sleep behavior disorder. J Sleep Res. 2008;17(Suppl.):103
- Consensus guidelines for the clinical and pathological diagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop. Neurology. 1996;47:1113–1124
- . The pathology of REM sleep behavior disorder with comorbid Lewy body dementia. Neurology. 2000;55:1730–1732
- . Nightmares without atonia as an early symptom of diffuse Lewy bodies disease. Arq Neuropsiquiatr. 2003;61:936–941
- REM sleep behavior and REM sleep without atonia in probable Alzheimer disease. Sleep. 2006;29:1321–1325
- . Neuropathological staging of Alzheimer-related changes. Acta Neuropathol. 1991;82:239–259
- . In: Jankovic J, Tolosa E editor. Parkinson's disease and movement disorders. Philadelphia: Lippincott Williams & Wilkins; 2002;p. 152–169
- . A first case of progressive supranuclear palsy and pre-clinical REM sleep behavior disorder presenting as inhibition of speech during wakefulness and somniloquy with phasic muscle twitching during REM sleep. Neurologia. 1996;11:304–306
- REM sleep behavior disorder and REM sleep without atonia in progressive supranuclear palsy. Sleep. 2005;28:349–354
- Sixel-Döring F, Schweitzer M, Mollenhauer B, Trenkwalder C. Polysomnographic findings, video-based sleep analysis and perception in progressive supranuclear palsy. Sleep Med, in press.
- Guadeloupean parkinsonism: a cluster of progressive supranuclear palsy-like taupathy. Brain. 2002;125:801–811
- REM sleep behavior disorder in patients with Guadeloupean parkinsonism, a taupathy. Sleep. 2007;30:1026–1032
- . Huntington's disease. In: Jankovic J, Tolosa E editor. Parkinson's disease and movement disorders. Philadelphia: Lippincott Williams & Wilkins; 2007;p. 212–227
- Rapid eye movement sleep disturbances in Huntington disease. Arch Neurol. 2008;68:482–488
- . Hereditary ataxias. In: Jankovic J, Tolosa E editor. Parkinson's disease and movement disorders. 5th ed.. Philadelphia: Lippincott Williams & Wilkins; 2007;p. 421–435
- . REM behavior disorder and excessive daytime somnolence in Machado–Joseph disease (SCA-3). Mov Disord. 2003;18:1520–1522
- . REM sleep behavior disorder and SCA-3 (Machado–Joseph disease). Neurology. 2003;60:148
- . REM sleep behavior disorder and vocal cord paralysis in Machado–Joseph disease. Mov Disord. 2003;18:1179–1183
- . Sleep disorders in autosomic dominant spinocerebellar ataxia: a genotype-phenotype study. Sleep. 2003;26(Suppl.):A353
- . Disturbance of rapid eye movement sleep in spinocerebellar ataxia type 2. Mov Disord. 2006;21:1751–1754
- . Association of REM sleep behavior disorder and neurodegenerative disease nay reflect an underlying synucleionopathy. Mov Disord. 2001;16:622–630
- . REM sleep behavior disorder. A dopaminergic deficiency disorder?. Neurology. 2003;61:1328–1329
- . Neuropathological spectrum of synucleinopathies. Mov Disord. 2003;18(Suppl. 6):S2–S12
- . Idiopathic rapid eye movement sleep behavior disorder is a harbinger of dementia with Lewy bodies. J Geriatr Psychiatry Neurol. 2002;15:195–199
- . Lewy body variant of Alzheimer's disease (AD) identified by postmortem ubiquitin staining in a previously reported case of AD associated with REM sleep behavior disorder. Biol Psychiatry. 1997;42:527–528
- . Absence of rapid eye movement sleep behavior disorder in 11 members of the pallidopontonigral degeneration kindred. Arch Neurol. 2006;63:268–272
- REM sleep behaviour disorder differentiates pure autonomic failure from multiple system atrophy with autonomic failure. J Neurol Neurosurg Psychiatry. 1998;64:683–685
- . REM sleep behavioral disorder in pure autonomic failure (PAF). Neurology. 2006;66:608–609
- . Lewy body-related alpha-synucleionopathy in the aged human brain. J Neural Transm. 2004;11:1219–1235
- . Rapid eye movement sleep behavior disorder preceding Parkinson's disease with therapeutic response to levodopa. Mov Disord. 1996;11:214–216
- . Use of pramipexole in REM sleep behavior disorder: results from a case series. Sleep Med. 2006;7:418–423
- A unique episode of RBD was triggered during surgery for Parkinson's disease. J Neurol Sci. 2007;253:73–76
- REM sleep behavior disorder is related to striatal monoaminergic deficit in MSA. Neurology. 2003;61:29–34
- Decreased phasic EMG activity during rapad eye movement sleep in treatment-naïve Parkinson's disease: effects of treatment with levodopa and progression of illness. Mov Disord. 2002;17:934–941
- . Sleep and sleepiness in patients with Parkinson's disease before and after dopaminergic treatment. Eur J Neurol. 2005;12:199–207
- . Activation by selegiline of REM sleep behavior in parkinsonism. W V Med J. 1995;91:101
- Effects of deep brain stimulation of the subthalamic nucleus on sleep architecture in parkinsonian patients. Sleep Med. 2004;5:207–210
- . A discrete pontine ischemic lesion could cause REM sleep behavior disorder. Neurology. 2000;55:894–895
- . Remitting REM sleep behavior disorder as the initial sign of multiple sclerosis. Sleep Med. 2002;3:437–439
- . REM sleep behaviour disorder associated with a neurinoma of the left pontocerebellar angle. J Neurol Neurosurg Psychiatry. 2002;72:821–822
- . Status dissociatus in multilacunar encephalopathy with median pontine lesion: a video-polygraphic presentation. J Sleep Res. 2006;15(Suppl. 1):212
- . REM sleep behavior disorder initiated by acute brainstem multiple sclerosis. Neurology. 2006;66:1277–1279
- . Prevalence of Restless Legs Syndrome and REM Sleep Behavior Disorder in Multiple Sclerosis. Mul Scler. 2007;13:805–808
- Xi Z, Luning W. REM sleep behavior disorder in a patient with a pontine stroke. Sleep Med, in press.
- Iranzo A, Aparicio J. A lesson from anatomy: focal brain lesions causing REM sleep behavior disorder. Sleep Med, in press.
- . Structural lesions associated with REM sleep behavior disorder. Sleep. 2008;31(Suppl.):A264
- . Localization of the GABAergic and non-GABAergic neurons projecting to the sublaterodorsal nucleus and potentially gating paradoxical sleep onset. Eur J Neurosci. 2003;18:1627–1639
- . A putative flip-flop switch for control of REM sleep. Nature. 2006;441:589–594
- . Impaired gabaergic and glycinergic neurotransmission induces RBD in transgenic mice. Sleep. 2007;30:A11
- . An endogenous glutamatergic drive onto somatic motoneurons contributes to the stereotypical pattern of muscle tone across the sleep-wake cycle. J Neurosci. 2008;28:4649–4660
- Paradoxical (REM) sleep genesis: The switch from an aminergic-cholinergic to GABAergic-glutamatergic hypothesis. J Physiol Paris. 2007;100:271–283
- . Evidence that glycine mediates the postsynaptic potentials that inhibit lumbar motoneurons during the atonia of active sleep. J Neurosci. 1989;9:743–751
- . Glycinercic and GABAA-mediated inhibition aof somatic motoneurons does not mediate rapid eye movement sleep mptor atonia. J Neurosci. 2008;28:3535–3545
- . Are all motoneurons created equal in the eyes of REM sleep and the mechanisms of muscle atonia?. Sleep. 2008;31:1479–1482
- . Glycine-mediated postsynaptic inhibition is responsible for REM sleep atonia. Sleep. 2008;31:1483–1486
- Chase MH. Confirmation of the consensus that glycinergic postsynaptic inhibition is responsible for the atonia of REM sleep. Sleep; 31:1487–491.
- . Unraveling the mechanisms of REM sleep atonia. Sleep. 2008;31:1492–1497
- . What causes muscle atonia in REM?. Sleep. 2008;31:1477–1478
- . Different behaviors during paradoxical sleep without atonia depend on pontine lesion site. Brain Res. 1982;239:81–105
- . Contrasting expressions of aggressive behavior related by lesions of the central nucleus of the amygdala during wakefulness and rapid eye movement sleep without atonia in cats. Behav Neurosci. 1998;112:589–602
- . Rapid eye movement sleep behavior disorder and potassium channel antibody-associated limbic encephalitis. Ann Neurol. 2006;59:178–182
- . Agrypinia excitata: clinical features and pathophysiologic implications. Sleep Med Rev. 2001;5:313–322
- Parkinson's disease: affection of brain stem nuclei controlling premotor and motor neurons of the somatomotor system. Acta Neuropathol. 2000;99:489–495
- . The pedunculopontine nucleus and Parkinson's disease. Brain. 2000;123:1767–1783
- . Immunocytochemical and ultrastructural studies of neuronal and oligodendroglial cytoplasmic inclusions in multiple system atrophy. Acta Neuropathol. 1992;83:453–460
- . Visual hallucinations in Lewy body disease relate to Lewy bodies in the temporal lobe. Brain. 2002;125:391–403
- . Dissociated states of wakefulness and sleep. Neurology. 1992;42(Suppl. 6):44–52
- . Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging. 2003;24:197–211
- . Idiopathic Parkinson's disease: possible routes by which vulnerable types may be subject to neuroinvasion by an unknown pathogen. J Neural Transm. 2003;110:517–536
- . The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: a critical analysis of alpha-synuclein staging. Neuropathol Appl Neurobiol. 2008;34:284–295
- . Alpha-synuclein pathology in Parkinson's disease and Alzheimer's disease brain: incidence and topographical distribution-a pilot study. Acta Neuropathol. 2003;106:191–201
- The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations. Brain. 2004;127:2657–2671
- . Alpha-synuclein pathology does not predict extrapyramidal symptoms or dementia. Ann Neurol. 2005;57:82–91
- . The frequency of Lewy bodies in a consecutive autopsy series. Clin Neuropathol. 1998;17:2004–2009
- . Alpha-synuclein pathology is highly dependent on the case selection. Neuropathol Appl Neurobiol. 2001;27:314–325
- Non-uniformity in the regional pattern of Lewy pathology in brains of dementia with Lewy bodies. Neuropathology. 2005;25:188–194
- . Grading of neuropathology in multiple system atrophy: proposal for a novel scale. Mov Disord. 2005;20(Suppl. 12):S29–S36
PII: S1087-0792(08)00129-9
doi: 10.1016/j.smrv.2008.11.003
© 2008 Elsevier Ltd. All rights reserved.
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Sleep Medicine Reviews
Volume 13, Issue 6
, Pages 385-401
, December 2009
